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Article

Interaction between glutathione S-transferase variants, maternal smoking and childhood wheezing changes with age.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Aug 2013

Wu Jiakai, Hankinson Jenny, Kopec-Harding Kamilla, Custovic Adnan, Simpson Angela

Abstract excerpt

BACKGROUND: Maternal smoking increases the risk of respiratory symptoms in children. Glutathione S-transferases (GSTs) detoxify xenobiotics from tobacco smoke, and functional polymorphism in GST gene(s) could predispose children to the detrimental effects of maternal smoking. Our objective was to investigate interactions between GST variants and maternal smoking in relation to the development of wheezing during...

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Source

Identifiers

PMID: 23879774
DOI: 10.1111/pai.12086

Genes

GSTP1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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