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Article

Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung function.

American journal of respiratory and critical care medicine - 1 Apr 2009

Breton Carrie V, Vora Hita, Salam Muhammad T, Islam Talat, Wenten Made, Gauderman W James, Van den Berg David, Berhane Kiros, Peters John M, Gilliland Frank D

Abstract excerpt

RATIONALE: The glutathione S-transferases (GSTs) are important detoxification enzymes. OBJECTIVES: To investigate effects of variants in GST mu genes on lung function and assess their interactions with tobacco smoke exposure. METHODS: In this prospective study, 14,836 lung function measurements were collected from 2,108 children who participated in two Southern California cohorts. For each child, tagging single...

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Source

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Identifiers

PMID: 19151192
DOI: 10.1164/rccm.200809-1384OC
PMCID: PMC2720124

Genes

GSTM2
GSTM3
GSTM4
FEV
GSTM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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