Article
Formation of D-alanyl-lipoteichoic acid is required for adhesion and virulence of Listeria monocytogenes.
Molecular microbiology - 1 Jan 2002
Abachin Eric, Poyart Claire, Pellegrini Elisabeth, Milohanic Eliane, Fiedler Franz, Berche Patrick, Trieu-Cuot Patrick
Abstract excerpt
The dlt operon of Gram-positive bacteria comprises four genes (dltA, dltB, dltC and dltD) that catalyse the incorporation of D-alanine residues into the cell wall-associated lipoteichoic acids (LTAs). In this work, we characterized the dlt operon of Listeria monocytogenes and constructed a D-Ala-deficient LTA mutant by inactivating the first gene (dltA) of this operon. The DltA- mutant did not show any...
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