Article
Listeria monocytogenes wall teichoic acid decoration in virulence and cell-to-cell spread.
Molecular microbiology - 1 Sept 2016
Spears Patricia A, Havell Edward A, Hamrick Terri S, Goforth John B, Levine Alexandra L, Abraham S Thomas, Heiss Christian, Azadi Parastoo, Orndorff Paul E
Abstract excerpt
Wall teichoic acid (WTA) comprises a class of glycopolymers covalently attached to the peptidoglycan of gram positive bacteria. In Listeria monocytogenes, mutations that prevent addition of certain WTA decorating sugars are attenuating. However, the steps required for decoration and the pathogenic process interrupted are not well described. We systematically examined the requirement for WTA galactosylation in a...
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