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Article

APOBEC3 Proteins Inhibit LINE‐1 Retrotransposition in the Absence of ORF1p Binding

1 Oct 2009

Abstract excerpt

Members of the apolipoprotein B mRNA editing complex polypeptide 1-like (APOBEC) family of enzymes exhibit inhibitory activity against a variety of exogenous and endogenous retroviruses including retrotransposons, such as long interspersed element 1 (LINE-1). Indeed, human APOBEC3A, APOBEC3B, and APOBEC3F inhibit retrotransposition of human LINE-1, mouse IAP and MusD retrotransposons. In our study, we examined...

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Identifiers

PMID: 19845642
DOI: 10.1111/j.1749-6632.2009.05006.x

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APOBEC3 Proteins Inhibit LINE‐1 Retrotransposition in the Absence of ORF1p BindingPMID 19845642Read ↗

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