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Article

Characterization of APOBEC3G binding to 7SL RNA.

Retrovirology - 2 Jul 2008

Bach Daniel, Peddi Shyam, Mangeat Bastien, Lakkaraju Asvin, Strub Katharina, Trono Didier

Abstract excerpt

Human APOBEC3 proteins are editing enzymes that can interfere with the replication of exogenous retroviruses such as human immunodeficiency virus (HIV), hepadnaviruses such as hepatitis B virus (HBV), and with the retrotransposition of endogenous retroelements such as long-interspersed nuclear elements (LINE) and Alu. Here, we show that APOBEC3G, but not other APOBEC3 family members, binds 7SL RNA, the common...

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Topics

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Share to Alu Elements
Share to APOBEC-3G Deaminase
Share to Cell Line

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytidine Deaminase

Share to Signal Recognition Particle

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Source

Open in PubMed Open full text

Identifiers

PMID: 18597676
DOI: 10.1186/1742-4690-5-54
PMCID: PMC2494554

Genes

SRP14
SRP19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of APOBEC3G binding to 7SL RNA.PMID 18597676Read ↗

7SL RNA mediates virion packaging of the antiviral cytidine deaminase APOBEC3G.Semantic proximity Read ↗

Interaction with 7SL RNA but not with HIV-1 genomic RNA or P bodies is required for APOBEC3F virion packaging.Semantic proximity Read ↗

Association of Potent Human Antiviral Cytidine Deaminases with 7SL RNA and Viral RNP in HIV-1 VirionsSemantic proximity Read ↗

Promiscuous RNA Binding Ensures Effective Encapsidation of APOBEC3 Proteins by HIV-1Semantic proximity Read ↗

Reduced APOBEC3H variant anti-viral activities are associated with altered RNA binding activities.Semantic proximity Read ↗

Cellular inhibitors of long interspersed element 1 and Alu retrotransposition.Semantic proximity Read ↗

Viral RNA Is Required for the Association of APOBEC3G with Human Immunodeficiency Virus Type 1 Nucleoprotein ComplexesSemantic proximity Read ↗

Virion packaging determinants and reverse transcription of SRP RNA in HIV-1 particlesSemantic proximity Read ↗

Amino-Terminal Region of the Human Immunodeficiency Virus Type 1 Nucleocapsid Is Required for Human APOBEC3G PackagingSemantic proximity Read ↗

Comparison of Cellular Ribonucleoprotein Complexes Associated with the APOBEC3F and APOBEC3G Antiviral ProteinsSemantic proximity Read ↗

APOBEC3G Incorporation into Human Immunodeficiency Virus Type 1 ParticlesSemantic proximity Read ↗

cis-Acting determinants of 7SL RNA packaging by HIV-1.Semantic proximity Read ↗

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