Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LOC387715/HTRA1 and complement factor H variants in patients with age-related macular degeneration seen at the mayo clinic.

Ophthalmic genetics - 1 Dec 2007

Pulido Jose S, Peterson Lisa M, Mutapcic Lejla, Bryant Sandra, Highsmith W Edward

Abstract excerpt

PURPOSE: To confirm association of the complement factor H allelic variant (CFH Y402H) and the LOC387715/HTRA1 (LOC387715 A69S) risk alleles with age-related macular degeneration (AMD). STUDY POPULATION: Study of 89 Caucasian patients with neovascular (exudative) AMD and 232 Caucasian controls. METHODS: The Y402H variant of CFH gene and A69S variant of LOC387715/HTRA1 gene locus were examined. RESULTS: For CFH,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Complement Factor H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Genetic Predisposition to Disease

Share to Macular Degeneration

Share to Minnesota

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 18161619
DOI: 10.1080/13816810701649617

Genes

HTRA1
CFH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LOC387715/HTRA1 and complement factor H variants in patients with age-related macular degeneration seen at the mayo clinic.PMID 18161619Read ↗

Analysis of complement factor H Y402H, LOC387715, HTRA1 polymorphisms and ApoE alleles with susceptibility to age-related macular degeneration in Hungarian patients.Semantic proximity Read ↗

Neovascular age-related macular degeneration and its association with LOC387715 and complement factor H polymorphism.Semantic proximity Read ↗

Age-related macular degeneration and association of CFH Y402H and LOC387715 A69S polymorphisms in a Turkish population.Semantic proximity Read ↗

Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration.Semantic proximity Read ↗

Association of CFH, LOC387715, and HTRA1 polymorphisms with exudative age-related macular degeneration in a northern Chinese population.Semantic proximity Read ↗

Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking.Semantic proximity Read ↗

Further support for the common variants in complement factor H (Y402H) and LOC387715 (A69S) genes as major risk factors for the exudative age-related macular degeneration.Semantic proximity Read ↗

Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab.Semantic proximity Read ↗

A pharmacogenetics study to predict outcome in patients receiving anti-VEGF therapy in age related macular degenerationSemantic proximity Read ↗

LOC387715/HTRA1 polymorphisms, smoking and combined effects on exudative age-related macular degeneration in a Korean population.Semantic proximity Read ↗

Multifactor effects and evidence of potential interaction between complement factor H Y402H and LOC387715 A69S in age-related macular degeneration.Semantic proximity Read ↗

Joint effects of polymorphisms in the HTRA1, LOC387715/ARMS2, and CFH genes on AMD in a Caucasian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.