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Article

Effect of the Gas6 c.834+7G>A polymorphism and the interaction of known risk factors on AMD pathogenesis in Hungarian patients.

PloS one - 1 Jan 2012

Losonczy Gergely, Vajas Attila, Takács Lili, Dzsudzsák Erika, Fekete Agnes, Márhoffer Eva, Kardos László, Ajzner Eva, Hurtado Begoña, de Frutos Pablo Garcia, Berta András, Balogh István

Abstract excerpt

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly in the developed world. Numerous genetic factors contribute to the development of the multifactorial disease. We performed a case-control study to assess the risk conferred by known and candidate genetic polymorphisms on the development of AMD. We searched for genetic interactions and for differences in dry and wet AMD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23209669
DOI: 10.1371/journal.pone.0050181
PMCID: PMC3510257

Genes

HTRA1
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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