Article
Association of CFH, LOC387715, and HTRA1 polymorphisms with exudative age-related macular degeneration in a northern Chinese population.
Molecular vision - 28 Jul 2008
Xu Yule, Guan Ning, Xu Jun, Yang Xiufen, Ma Kai, Zhou Haiying, Zhang Feng, Snellingen Torkel, Jiao Yiqun, Liu Xipu, Wang Ningli, Liu Ningpu
Abstract excerpt
PURPOSE: Variants in complement factor H (CFH), the hypothetical LOC387715, and the high-temperature requirement A-1 (HTRA1) genes have been reported to be associated with age-related macular degeneration (AMD). The purpose of this study was to investigate the association of reported common single-nucleotide polymorphisms (SNPs) in CFH, LOC387715, and HTRA1 with exudative AMD in a northern Chinese population....
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