Article
Foxg1 is required for proper separation and formation of sensory cristae during inner ear development.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2009
Hwang Chan Ho, Simeone Antonio, Lai Eseng, Wu Doris K
Abstract excerpt
The vestibular portion of the inner ear, the three semicircular canals and their sensory cristae, is responsible for detecting angular head movements. It was proposed that sensory cristae induce formation of their non-sensory components, the semicircular canals. Here, we analyzed the inner ears of Foxg1(-/-) mouse mutants, which display vestibular defects that are in conflict with the above model. In Foxg1(-/-)...
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