Article
Foxg1 is required for morphogenesis and histogenesis of the mammalian inner ear.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Sept 2006
Pauley Sarah, Lai Eseng, Fritzsch Bernd
Abstract excerpt
The forkhead genes are involved in patterning, morphogenesis, cell fate determination, and proliferation. Several Fox genes (Foxi1, Foxg1) are expressed in the developing otocyst of both zebrafish and mammals. We show that Foxg1 is expressed in most cell types of the inner ear of the adult mouse and that Foxg1 mutants have both morphological and histological defects in the inner ear. These mice have a shortened...
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