Article
No association of VEGF polymorphims with Alzheimer's disease.
Neuromolecular medicine - 1 Sept 2010
Landgren Sara, Palmér Mona Seibt, Skoog Ingemar, Minthon Lennart, Wallin Anders, Andreasen Niels, Zetterberg Madeleine, Blennow Kaj, Zetterberg Henrik
Abstract excerpt
The vascular hypothesis of Alzheimer's disease (AD) has brought the vascular endothelial growth factor (VEGF) into focus. The genomic region including the VEGF gene has been linked to AD and single nucleotide polymorphisms (SNPs) of the VEGF have in previous studies been associated with AD risk. To further evaluate these findings, we genotyped two SNPs in the VEGF gene (rs699947 [-2578]) and rs1570360 [-1154]) by...
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