Article
Haplotype analysis of single nucleotide polymorphisms in VEGF gene for vascular dementia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2006
Kim Younyoung, Nam Yu Jin, Lee Chaeyoung
Abstract excerpt
A case-control study was performed to identify single nucleotide variants of vascular endothelial growth factor (VEGF) gene associated with vascular dementia. Seven SNPs in promoter, 5'-UTR, 3'-UTR, and introns of VEGF gene were identified in 24 Koreans. Three of them, -1154G/A, -7C/T, and 13553C/T, were selected based on allele frequency and linkage disequilibrium (LD), and genotyped in 207 vascular dementia...
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