Article
Vascular endothelial growth factor gene variability is associated with increased risk for AD.
Annals of neurology - 1 Mar 2005
Del Bo Roberto, Scarlato Marina, Ghezzi Serena, Martinelli Boneschi Filippo, Fenoglio Chiara, Galbiati Sara, Virgilio Roberta, Galimberti Daniela, Galimberti Gloria, Crimi Marco, Ferrarese Carlo, Scarpini Elio, Bresolin Nereo, Comi Giacomo P
Abstract excerpt
Converging evidence points to a pivotal role of vascular endothelial growth factor (VEGF) in neuronal protection and a lack of its activity in neurodegenerative disorders. To investigate this possible association, we screened the VEGF gene promoter for various well-known single-nucleotide polymorphisms in a series of 249 consecutively recruited Italian patients with sporadic Alzheimer's disease (AD). Genetic...
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