Article
VEGF genetic variability is associated with increased risk of developing Alzheimer's disease.
Journal of the neurological sciences - 15 Aug 2009
Del Bo Roberto, Ghezzi Serena, Scarpini Elio, Bresolin Nereo, Comi Giacomo Pietro
Abstract excerpt
Specific polymorphisms within the vascular endothelial growth factor (VEGF) gene promoter region are of particular interest: VEGF variability has been associated with increased risk of developing a wide variety of disorders from diabetes to neurodegenerative diseases, suggesting functions not confined to its originally described vascular effects. A hypothetical loss of the VEGF-mediated neuroprotective effect has...
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