Article
VEGF gene and phenotype relation with Alzheimer's disease and mild cognitive impairment.
Rejuvenation research - 1 Jan 2006
Chiappelli Martina, Borroni Barbara, Archetti Silvana, Calabrese Elena, Corsi Massimiliano M, Franceschi Massimo, Padovani Alessandro, Licastro Federico
Abstract excerpt
BACKGROUND: The expression of vascular endothelial growth factor (VEGF) represents one potential mechanism whereby vascular and Alzheimer's disease (AD) pathologies are related. The authors investigated whether AD cases, especially those having a rapid cognitive decline, more commonly carried a functional promoter gene variant for VEGF (-2578C/A) and showed elevated plasma levels of Vegf. In addition, the authors...
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