Article
Hermaphrodism and sex reversal associated with the dominant hemimelia mutation in XY mice.
Proceedings of the Japan Academy. Series B, Physical and biological sciences - 1 Jan 2009
Suto Jun-ichi
Abstract excerpt
After two generations of backcrossing six different Y-consomic strains onto a C57BL/6J inbred mouse strain with a dominant hemimelia (Dh) mutation, a small percentage of Dh/+ males containing a Y chromosome from the AKR/J or RF/J strain showed hermaphrodism; they lacked the right testis and had an ovary and a uterus instead. Approximately 15% of Dh/+ females considered to be phenotypically normal had the Sry gene...
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