Article
Sex-determining genes on mouse autosomes identified by linkage analysis of C57BL/6J-YPOS sex reversal.
Nature genetics - 1 Oct 1996
Eicher E M, Washburn L L, Schork N J, Lee B K, Shown E P, Xu X, Dredge R D, Pringle M J, Page D C
Abstract excerpt
A powerful approach for identifying mammalian primary (gonadal) sex determination genes is the molecular genetic analyses of sex reversal conditions (that is, XX individuals with testicular tissue and XY individuals with ovarian tissue). Here we determined the number and chromosomal location of a...
Topics
- Animals
- Chromosome Mapping
- Crosses, Genetic
- DNA-Binding Proteins
- Disorders of Sex Development
- Female
- Genes
- Genetic Linkage
- Genotype
- Gonads
- Male
- Mice
- Mice, Inbred C57BL
- Muridae
- Nuclear Proteins
- Sex Differentiation
- Sex-Determining Region Y Protein
- Transcription Factors
