Article
Distribution of the molossinus allele of Sry, the testis-determining gene, in wild mice.
Molecular biology and evolution - 1 Nov 1994
Nagamine C M, Shiroishi T, Miyashita N, Tsuchiya K, Ikeda H, Takao N, Wu X L, Jin M L, Wang F S, Kryukov A P
Abstract excerpt
When the Y chromosome of the laboratory inbred mouse strain C57BL/6 (B6) is replaced by the Y of certain strains of Mus musculus domesticus, testis determination fails and all XY fetuses develop either as hermaphrodites or XY females (XY sex reversal). This suggests the presence of at least two alleles of Sry, the male-determining gene on the Y:M. m. domesticus and B6. The B6 Y chromosome is derived from the...
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