Article
The dominant white spotting oncogene allele Kit(W-42J) exacerbates XY(DOM) sex reversal.
Development (Cambridge, England) - 1 Nov 1996
Nagamine C M, Carlisle C
Abstract excerpt
The Y chromosome from certain populations of M. m. domesticus is incapable of normal testis determination in the B6 inbred strain resulting in XY hermaphrodites or XY females (XY(DOM) sex reversal). B6 consomic strains have been developed with either transient (B6-Y(AKR)) or severe (B6-Y(TIR)) XY...
Topics
- Alleles
- Animals
- Cell Differentiation
- DNA-Binding Proteins
- Gene Expression Regulation, Developmental
- Genes, Dominant
- Genotype
- Homozygote
- Male
- Mice
- Mice, Inbred C57BL
- Nuclear Proteins
- Proto-Oncogene Proteins c-kit
- Sex Determination Analysis
- Sex-Determining Region Y Protein
- Testis
- Time Factors
- Transcription Factors