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Article

Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.

PLoS genetics - 1 Oct 2009

Wheeler Heather E, Metter E Jeffrey, Tanaka Toshiko, Absher Devin, Higgins John, Zahn Jacob M, Wilhelmy Julie, Davis Ronald W, Singleton Andrew, Myers Richard M, Ferrucci Luigi, Kim Stuart K

Abstract excerpt

Kidneys age at different rates, such that some people show little or no effects of aging whereas others show rapid functional decline. We sequentially used transcriptional profiling and expression quantitative trait loci (eQTL) mapping to narrow down which genes to test for association with kidne...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetics, Aging, and Longevity in Model Organisms

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Source

Open in PubMed Open full text

Identifiers

PMID: 19834535
DOI: 10.1371/journal.pgen.1000685
PMCID: PMC2752811

Genes

MMP20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19834535-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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