Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Proteomic and transcriptomic profiling reveal different aspects of aging in the kidney

9 Mar 2021

Abstract excerpt

Little is known about the molecular changes that take place in the kidney during the aging process. In order to better understand these changes, we measured mRNA and protein levels in genetically diverse mice at different ages. We observed distinctive change in mRNA and protein levels as a function of age. Changes in both mRNA and protein are associated with increased immune infiltration and decreases in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Kidney Disease and Diabetes
Share to Diet and metabolism studies
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33687326
DOI: 10.7554/elife.62585

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Proteomic and transcriptomic profiling reveal different aspects of aging in the kidneyPMID 33687326Read ↗

A Transcriptional Profile of Aging in the Human KidneySemantic proximity Read ↗

Aging and senescence-associated analysis of the aged kidney glomerulus highlights the role of mesangial cells in renal agingSemantic proximity Read ↗

Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profilingSemantic proximity Read ↗

Genome-wide transcript and protein analysis reveals distinct features of aging in the mouse heartSemantic proximity Read ↗

Proteomic Profiling of Aging in Glomeruli of Mice by using Two-Dimensional Differential Gel ElectrophoresisSemantic proximity Read ↗

What have we learned on aging from omics studies?Semantic proximity Read ↗

Altered lipid metabolism in the aging kidney identified by three layered omic analysis.Semantic proximity Read ↗

Predict the role of lncRNA in kidney aging based on RNA sequencingSemantic proximity Read ↗

Kidney Aging and Chronic Kidney DiseaseSemantic proximity Read ↗

Upregulated PD-1 Signaling is an Important Antagonist to Glomerular Health in Aged KidneysSemantic proximity Read ↗

Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomicsSemantic proximity Read ↗

Aging is associated with a systemic length-driven transcriptome imbalanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.