Article
Short report: insertion variant in intron 9, but not microsatellite in intron 2, of the insulin receptor gene is associated with essential hypertension.
Journal of hypertension - 1 Nov 1993
Zee R Y, Lou Y K, Morris B J
Abstract excerpt
OBJECTIVE: To determine whether a microsatellite polymorphism of the insulin receptor gene (INSR) is associated with essential hypertension, as has been demonstrated previously for an Rsal restriction fragment length polymorphism (RFLP), and to examine blood pressure and plasma lipid profiles in relation to genotype. DESIGN AND METHODS: The study involved 75 Caucasian, non-diabetic hypertensive patients whose...
Topics
- Adult
- Alleles
- Genotype
- Humans
- Hypertension
- Introns
- Linkage Disequilibrium
- Lipids
- Polymorphism, Genetic
- Receptor, Insulin
