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Article

Lung adenocarcinoma with EGFR amplification has distinct clinicopathologic and molecular features in never-smokers.

Cancer research - 1 Nov 2009

Sholl Lynette M, Yeap Beow Y, Iafrate A John, Holmes-Tisch Alison J, Chou Yi-Ping, Wu Ming-Tsang, Goan Yih-Gang, Su Li, Benedettini Elisa, Yu Jian, Loda Massimo, Jänne Pasi A, Christiani David C, Chirieac Lucian R

Abstract excerpt

In a subset of lung adenocarcinomas, the epidermal growth factor receptor (EGFR) is activated by kinase domain mutations and/or gene amplification, but the interaction between the two types of abnormalities is complex and unclear. For this study, we selected 99 consecutive never-smoking women of...

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Share to Adenocarcinoma, Bronchiolo-Alveolar
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19826035
DOI: 10.1158/0008-5472.CAN-09-2477
PMCID: PMC2783286

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19826035-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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