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Article

Comprehensive Molecular Analysis of NSCLC; Clinicopathological Associations.

PloS one - 1 Jan 2015

Chatziandreou Ilenia, Tsioli Panagiota, Sakellariou Stratigoula, Mourkioti Ioanna, Giannopoulou Ioanna, Levidou Georgia, Korkolopoulou Penelope, Patsouris Efstratios, Saetta Angelica A

Abstract excerpt

BACKGROUND: Selection of NSCLC patients for targeted therapy is currently based upon the presence of sensitizing mutations in EGFR and EML4/ALK translocations. The heterogeneity of molecular alterations in lung cancer has led to the ongoing discovery of potential biomarkers and targets in order to improve survival. AIM: This study aimed to detect alterations in EGFR, KRAS, BRAF, PIK3CA, MET-gene copy number and...

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Share to Class I Phosphatidylinositol 3-Kinases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Phosphatidylinositol 3-Kinases

Share to Proto-Oncogene Proteins B-raf

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Source

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Identifiers

PMID: 26208325
DOI: 10.1371/journal.pone.0133859
PMCID: PMC4514742

Genes

EGFR
ALK
KRAS
BRAF
MET
EML4
TTF1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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