Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Higher dosage of the epidermal growth factor receptor mutant allele in lung adenocarcinoma correlates with younger age, stage IV at presentation, and poorer survival.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Aug 2011

Oakley Gerard J, Chiosea Simion I

Abstract excerpt

INTRODUCTION: The clinical significance of epidermal growth factor receptor (EGFR) mutant allele specific imbalance (MASI) in lung adenocarcinomas is unknown. METHODS: EGFR MASI was characterized by sequencing electropherograms (SEs) and EGFR fluorescence in situ hybridization (FISH) in 96 prospectively tested lung adenocarcinoma patients with a median follow-up of 20 months (all cases were EGFR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to DNA, Neoplasm

Share to ErbB Receptors

Share to In Situ Hybridization, Fluorescence

Share to Neoplasm Staging

Share to Survival Rate

Source

Identifiers

PMID: 21587084
DOI: 10.1097/JTO.0b013e31821d41af

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Higher dosage of the epidermal growth factor receptor mutant allele in lung adenocarcinoma correlates with younger age, stage IV at presentation, and poorer survival.PMID 21587084Read ↗

KRAS mutant allele-specific imbalance in lung adenocarcinoma.Semantic proximity Read ↗

EGFR mutant allelic-specific imbalance assessment in routine samples of non-small cell lung cancer.Semantic proximity Read ↗

Epidermal growth factor receptor abnormalities in lung cancer. Pathogenetic and clinical implications.Semantic proximity Read ↗

Mutant allele specific imbalance in oncogenes with copy number alterations: Occurrence, mechanisms, and potential clinical implications.Semantic proximity Read ↗

Mutational Damages in Malignant Lung Tumors.Semantic proximity Read ↗

Lung adenocarcinoma with EGFR amplification has distinct clinicopathologic and molecular features in never-smokers.Semantic proximity Read ↗

High frequency of Exon 20 S768I <i>EGFR</i> mutation detected in malignant pleural effusions: a poor prognosticator of NSCLC?Semantic proximity Read ↗

EGFR mutation testing on cytological and histological samples in non-small cell lung cancer: a Polish, single institution study and systematic review of European incidence.Semantic proximity Read ↗

Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells.Semantic proximity Read ↗

Genomic profiles specific to patient ethnicity in lung adenocarcinoma.Semantic proximity Read ↗

Correlation of EGFR mutations with chromosomal alterations and expression of EGFR, ErbB3 and VEGF in tumor samples of lung adenocarcinoma patients.Semantic proximity Read ↗

Chromosomal imbalances in lung adenocarcinomas with or without mutations in the epidermal growth factor receptor gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.