Article
Distinct clinical features and outcomes in never-smokers with nonsmall cell lung cancer who harbor EGFR or KRAS mutations or ALK rearrangement.
Cancer - 1 Feb 2012
Kim Hye Ryun, Shim Hyo Sup, Chung Jin-Haeng, Lee Young Joo, Hong Yun Kyoung, Rha Sun Young, Kim Se Hoon, Ha Sang-Jun, Kim Se Kyu, Chung Kyung Young, Soo Ross, Kim Joo Hang, Cho Byoung Chul
Abstract excerpt
BACKGROUND: The objectives of this study were to determine the proportions of major oncogenic alterations and to examine survival in genotype-specific subsets of never-smokers with nonsmall cell lung cancer (NSCLC). METHODS: The authors concurrently analyzed mutations in the epidermal growth factor receptor (EGFR) and v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) genes and investigated anaplastic...
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