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Article

Bias correction of estimates of familial risk from population-based cohort studies.

International journal of epidemiology - 1 Feb 2010

Leu Monica, Czene Kamila, Reilly Marie

Abstract excerpt

BACKGROUND: In addition to guiding molecular epidemiology investigations, estimates of the increased risk of disease in relatives of affected persons are also important for screening and counselling decisions. Since precise estimation of such familial risks (FRs) requires large sample sizes, many of the estimates in common use have been obtained from historical electronic records of disease in entire populations,...

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PMID: 19825986
DOI: 10.1093/ije/dyp304

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