Article
Familial relative risk estimates for use in epidemiologic analyses.
American journal of epidemiology - 1 Oct 2006
Yasui Yutaka, Newcomb Polly A, Trentham-Dietz Amy, Egan Kathleen M
Abstract excerpt
Commonly used crude measures of disease risk or relative risk in a family, such as the presence/absence of disease or the number of affected relatives, do not take into account family structures and ages at disease occurrence. The Family History Score incorporates these factors and has been used widely in epidemiology. However, the Family History Score is not an estimate of familial relative risk; rather, it...
Topics
- Aged
- Bayes Theorem
- Breast Neoplasms
- Female
- Genetic Predisposition to Disease
- Humans
- Middle Aged
- Poisson Distribution
- Regression Analysis
- Risk Assessment