Article
Regulation of cell proliferation and wing development by Drosophila SIN3 and String.
Mechanisms of development - 1 Jan 2000
Swaminathan Aishwarya, Pile Lori A
Abstract excerpt
The transcriptional corepressor SIN3 is an essential gene in metazoans. In cell culture experiments, loss of SIN3 leads to defects in cell proliferation. Whether and how SIN3 may regulate the cell cycle during development has not been explored. To gain insight into this relationship, we have generated conditional knock down of Drosophila SIN3 and analyzed effects on growth and development in the wing imaginal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
