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Article

The Drosophila Sin3 gene encodes a widely distributed transcription factor essential for embryonic viability.

Development genes and evolution - 1 Nov 1998

Pennetta G, Pauli D

Abstract excerpt

Expression of many mammalian genes is activated by the binding of heterodimers of the Myc and Max proteins to specific DNA sequences called the E-boxes. Transcription of the same genes is repressed upon binding to the same sequences of complexes composed of Max, Mad/Mxi1, the co-repressors Sin3 and N-CoR, and the histone deacetylase Rpd3. Max-Mad/Mxi1 heterodimers, which bind to E-boxes in absence of...

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PMID: 9799435
DOI: 10.1007/s004270050212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The Drosophila Sin3 gene encodes a widely distributed transcription factor essential for embryonic viability.PMID 9799435Read ↗

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The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs.Semantic proximity Read ↗

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