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Article

A genetic screen to identify components of the sina signaling pathway in Drosophila eye development.

Genetics - 1 Jan 1998

Neufeld T P, Tang A H, Rubin G M

Abstract excerpt

Specification of the R7 photoreceptor cell in the developing Drosophila eye requires the seven in absentia (sina) gene. We demonstrate that ectopic expression of sina in all cells behind the morphogenetic furrow disrupts normal eye development during pupation, resulting in a severely disorganized adult eye. Earlier events of cell fate specification appear unaffected. A genetic screen for dominant enhancers and...

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Identifiers

PMID: 9475739
DOI: 10.1093/genetics/148.1.277
PMCID: PMC1459784

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