Article
An update on the pathogenesis of cholesterol gallstone disease.
Current opinion in gastroenterology - 1 Mar 2018
Di Ciaula Agostino, Wang David Q-H, Portincasa Piero
Abstract excerpt
PURPOSE OF REVIEW: Gallstone disease is a major epidemiologic and economic burden worldwide, and the most frequent form is cholesterol gallstone disease. RECENT FINDINGS: Major pathogenetic factors for cholesterol gallstones include a genetic background, hepatic hypersecretion of cholesterol, and supersaturated bile which give life to precipitating cholesterol crystals that accumulate and grow in a sluggish...
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