Article
Ribosomal DNA contributes to global chromatin regulation.
Proceedings of the National Academy of Sciences of the United States of America - 20 Oct 2009
Paredes Silvana, Maggert Keith A
Abstract excerpt
The 35S ribosomal RNA genes (rDNA) are organized as repeated arrays in many organisms. Epigenetic regulation of transcription of the rRNA results in only a subset of copies being transcribed, making rDNA an important model for understanding epigenetic chromatin modification. We have created an allelic series of deletions within the rDNA array of the Drosophila Y chromosome that affect nucleolus size and...
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