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Article

Genetic variation in recalcitrant repetitive regions of the Drosophila melanogaster genome.

Genome research - 2 Sept 2025

Shukla Harsh G, Chakraborty Mahul, Emerson J J

Abstract excerpt

Many essential functions of organisms are encoded in highly repetitive genomic regions, including histones involved in DNA packaging, centromeres that are core components of chromosome segregation, ribosomal RNA comprising the protein translation machinery, telomeres that ensure chromosome integrity, piRNA clusters encoding host defenses against selfish elements, and virtually the entire Y Chromosome. These...

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Identifiers

PMID: 40670076
DOI: 10.1101/gr.280728.125
PMCID: PMC12400953

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