Article
Allelic inactivation of rDNA loci.
Genes & development - 15 Oct 2009
Schlesinger Sharon, Selig Sara, Bergman Yehudit, Cedar Howard
Abstract excerpt
Human cells contain several hundred ribosomal genes (rDNA) that are clustered into nucleolar organizer regions (NORs) on the short arms of five different acrocentric chromosomes. Only approximately 50% of the gene copies are actually expressed in somatic cells. Here, we used a new cytological tec...
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