Crossover/noncrossover differentiation, synaptonemal complex formation, and regulatory surveillance at the leptotene/zygotene transition of meiosis.

doi:10.1016/s0092-8674(04)00292-2

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Article

Crossover/noncrossover differentiation, synaptonemal complex formation, and regulatory surveillance at the leptotene/zygotene transition of meiosis.

Cell - 2 Apr 2004

Börner G Valentin, Kleckner Nancy, Hunter Neil

Abstract excerpt

Yeast mutants lacking meiotic proteins Zip1, Zip2, Zip3, Mer3, and/or Msh5 (ZMMs) were analyzed for recombination, synaptonemal complex (SC), and meiotic progression. At 33 degrees C, recombination-initiating double-strand breaks (DSBs) and noncrossover products (NCRs) form normally while formation of single-end invasion strand exchange intermediates (SEIs), double Holliday junctions, crossover products (CRs),...

Topics

Chromosome Segregation
Chromosomes
DNA, Cruciform
DNA, Single-Stranded
Genes, cdc
Meiosis
Mutation
Phenotype
Recombination, Genetic
Saccharomyces
Synaptonemal Complex
Temperature

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Identifiers

PMID: 15066280
DOI: 10.1016/s0092-8674(04)00292-2

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