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Article

Meiotic chromosome synapsis-promoting proteins antagonize the anti-crossover activity of sgs1.

PLoS genetics - 22 Sept 2006

Jessop Lea, Rockmill Beth, Roeder G Shirleen, Lichten Michael

Abstract excerpt

Sgs1, the budding yeast homolog of the mammalian BLM helicase, has been implicated in preventing excess recombination during both vegetative growth and meiosis. Most meiotic crossover (CO) recombination requires full function of a set of yeast proteins (Zip1, Zip2, Zip3, Zip4/Spo22, Mer3, Msh4, and Msh5, termed the SIC or ZMM proteins) that are also required for homologous chromosome synapsis. We report here...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17002499
DOI: 10.1371/journal.pgen.0020155
PMCID: PMC1570379

Genes

BLM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Meiotic chromosome synapsis-promoting proteins antagonize the anti-crossover activity of sgs1.PMID 17002499Read ↗

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