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In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice

22 Nov 2017

Abstract excerpt

Mitochondria are the powerhouses of cells and produce cellular energy in the form of ATP. Mitochondrial dysfunction contributes to biological aging and a wide variety of disorders including metabolic diseases, premature aging syndromes, and neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD). Maintenance of mitochondrial health depends on mitochondrial biogenesis and the...

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PMID: 29286376
DOI: 10.3791/56301

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