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Role of Prohibitins in Aging and Therapeutic Potential Against Age-Related Diseases

29 Oct 2021

Abstract excerpt

A decline in mitochondrial function has long been associated with age-related health decline. Several lines of evidence suggest that interventions that stimulate mitochondrial autophagy (mitophagy) can slow aging and prolong healthy lifespan. Prohibitins (PHB1 and PHB2) assemble at the mitochondrial inner membrane and are critical for mitochondrial homeostasis. In addition, prohibitins (PHBs) have diverse roles...

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Share to ATP Synthase and ATPases Research
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PMID: 34868199
DOI: 10.3389/fgene.2021.714228

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