Article
Can mutational GC-pressure create new linear B-cell epitopes in herpes simplex virus type 1 glycoprotein B?
Immunological investigations - 1 Jan 2009
Khrustalev Vladislav Victorovich
Abstract excerpt
We showed that GC-content of nucleotide sequences coding for linear B-cell epitopes of herpes simplex virus type 1 (HSV1) glycoprotein B (gB) is higher than GC-content of sequences coding for epitope-free regions of this glycoprotein (G + C = 73 and 64%, respectively). Linear B-cell epitopes have been predicted in HSV1 gB by BepiPred algorithm ( www.cbs.dtu.dk/services/BepiPred ). Proline is an acrophilic amino...
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