Article
[Mutational pressure in genomes of alphaherpesviruses infecting human].
Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 Jan 2008
Khrustalev V V, Barkovskiĭ E V
Abstract excerpt
Genomes of the herpes simplex viruses are extremely enriched with GC. Elevated G+C level in genomes of the simplex viruses is a result of their long-term evolution under the influence of the mutational pressure. We counted the rates of nucleotide substitutions from gene coding major capsid protein (MCP) (G+C = 0.68, 3GC = 0.89) of human simplex virus 1 (HSV-1) to the MCP gene (G+C = 0.70, 3GC = 0.91) of HSV-2...
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