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Article

Levels of HIV1 gp120 3D B-cell epitopes mutability and variability: searching for possible vaccine epitopes.

Immunological investigations - 1 Jan 2010

Khrustalev Vladislav Victorovich

Abstract excerpt

We used a DiscoTope 1.2 (http://www.cbs.dtu.dk/services/DiscoTope/), Epitopia (http://epitopia.tau.ac.il/) and EPCES (http://www.t38.physik.tu-muenchen.de/programs.htm) algorithms to map discontinuous B-cell epitopes in HIV1 gp120. The most mutable nucleotides in HIV genes are guanine (because of G to A hypermutagenesis) and cytosine (because of C to U and C to A mutations). The higher is the level of guanine and...

Read the complete abstract on PubMed

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Share to Antigenic Variation
Share to Conserved Sequence
Share to Databases, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Viral

Share to Epitope Mapping

Share to Epitopes, B-Lymphocyte

Share to HIV Envelope Protein gp120

Share to Viral Vaccines

Source

Identifiers

PMID: 20653424
DOI: 10.3109/08820131003706313

Genes

PAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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