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Article

Characterization of the antigenic structure of herpes simplex virus type 1 glycoprotein C through DNA sequence analysis of monoclonal antibody-resistant mutants.

Journal of virology - 1 Feb 1990

Wu C T, Levine M, Homa F, Highlander S L, Glorioso J C

Abstract excerpt

Earlier studies of a group of monoclonal antibody-resistant (mar) mutants of herpes simplex virus type 1 glycoprotein C (gC) operationally defined two distinct antigenic sites on this molecule, each consisting of numerous overlapping epitopes. In this report, we further define epitopes of gC by s...

Topics

Animals
Antibodies, Monoclonal
Antigens, Viral
DNA, Viral
Epitopes
Genes, Viral
Mutation
Phenotype
Protein Conformation
Restriction Mapping
Simplexvirus
Software

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Vero Cells

Viral Envelope Proteins

Viral Structural Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 1688628
DOI: 10.1128/JVI.64.2.856-863.1990
PMCID: PMC249181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1688628-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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