Article
An in-silico study of alphaherpesviruses ICP0 genes: positive selection or strong mutational GC-pressure?
IUBMB life - 1 Jul 2008
Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich
Abstract excerpt
The purpose of our work was to analyze the case of the strong mutational GC-pressure influence on the ratio between nonsynonymous (DN) and synonymous (DS) distances (DN/DS ratio). We have used as the material the genes coding for ICP0 from five completely sequenced genomes of simplexviruses. DN/DS ratio, total GC-content (G + C), and GC-content in first, second, and third codon positions (1GC, 2GC, and 3GC,...
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