Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence That Nucleosomes Inhibit Mismatch Repair in Eukaryotic Cells

7 Oct 2009

Abstract excerpt

The influence of chromatin structure on DNA metabolic processes, including DNA replication and repair, has been a matter of intensive studies in recent years. Although the human mismatch repair (MMR) reaction has been reconstituted using purified proteins, the influence of chromatin structure on human MMR is unknown. This study examines the interaction between human MutSalpha and a mismatch located within a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair Mechanisms
Share to Genetic factors in colorectal cancer
Share to Genomics and Chromatin Dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19808662
DOI: 10.1074/jbc.m109.049874

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence That Nucleosomes Inhibit Mismatch Repair in Eukaryotic CellsPMID 19808662Read ↗

CAF-I-dependent control of degradation of the discontinuous strands during mismatch repairSemantic proximity Read ↗

The MutSα-Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch RepairSemantic proximity Read ↗

Intrinsically disordered regions regulate both catalytic and non-catalytic activities of the MutLα mismatch repair complex.Semantic proximity Read ↗

Mispair-bound human MutS–MutL complex triggers DNA incisions and activates mismatch repairSemantic proximity Read ↗

The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch.Semantic proximity Read ↗

Dynamic human MutSα–MutLα complexes compact mismatched DNASemantic proximity Read ↗

The alternating ATPase domains of MutS control DNA mismatch repair.Semantic proximity Read ↗

Interplay between mismatch repair and chromatin assemblySemantic proximity Read ↗

Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repair.Semantic proximity Read ↗

Mismatch repair protein hMSH2–hMSH6 recognizes mismatches and forms sliding clamps within a D-loop recombination intermediateSemantic proximity Read ↗

Mutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair.Semantic proximity Read ↗

Contribution of Human Mlh1 and Pms2 ATPase Activities to DNA Mismatch RepairSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.