Article
Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population.
Diabetes - 1 Oct 2007
Chang Yi-Cheng, Chang Tien-Jyun, Jiang Yi-Der, Kuo Shan-Shan, Lee Kuan-Ching, Chiu Ken C, Chuang Lee-Ming
Abstract excerpt
OBJECTIVE: Genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene is one of the few validated genetic variants with large effects on the risk of type 2 diabetes in the populations of European ancestry. In this study, we aimed to explore the effect of the TCF7L2 polymorphisms in a Han Chinese population. RESEARCH DESIGN AND METHODS: We genotyped 20 single nucleotide polymorphisms (SNPs) across...
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