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Article

Genetic variants of TCF7L2 are associated with insulin resistance and related metabolic phenotypes in Taiwanese adolescents and Caucasian young adults.

The Journal of clinical endocrinology and metabolism - 1 Sept 2009

Liu Pi-Hua, Chang Yi-Cheng, Jiang Yi-Der, Chen Wei J, Chang Tien-Jyun, Kuo Shan-Shan, Lee Kuan-Ching, Hsiao Po-Chang, Chiu Ken C, Chuang Lee-Ming

Abstract excerpt

OBJECTIVES: The effect of TCF7L2 rs7903146 on glucose homeostasis is considered primarily due to impaired insulin secretion in European populations. Because we previously demonstrated that TCF7L2 rs290487 near the 3' end of TCF7L2 was significantly associated with type 2 diabetes (T2D) in Taiwanese subjects, we aimed to investigate potential mechanisms underlying the associations of rs290487 with T2D. METHODS:...

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Source

Identifiers

PMID: 19509102
DOI: 10.1210/jc.2009-0609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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