Article
Efficient transposition of Tol2 in the mouse germline.
Genetics - 1 Dec 2009
Keng Vincent W, Ryan Barbara J, Wangensteen Kirk J, Balciunas Darius, Schmedt Christian, Ekker Stephen C, Largaespada David A
Abstract excerpt
Insertional mutagenesis screens play an integral part in the annotating of functional data for all sequenced genes in the postgenomic era. Chemical mutagenesis screens are highly efficient but identifying the causative gene can be a laborious task. Other mutagenesis platforms, such as transposable elements, have been successfully applied for insertional mutagenesis screens in both the mouse and rat. However,...
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