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Article

ENU mutagenesis in mice.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008

Georgel Philippe, Du Xin, Hoebe Kasper, Beutler Bruce

Abstract excerpt

Forward genetics has led to many "breakthrough" discoveries, and with the mouse genome almost fully sequenced, the creation of phenotypes through random germline mutagenesis has become an efficient means by which to find the function of yet undescribed genes. In this chapter, we will provide a practical guideline for performing germline mutagenesis in mice. In particular, we will focus on the application of this...

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PMID: 18370145
DOI: 10.1007/978-1-59745-570-1_1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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